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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EFHD2
All Species:
17.27
Human Site:
S76
Identified Species:
31.67
UniProt:
Q96C19
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96C19
NP_077305.2
240
26697
S76
I
G
E
P
Q
S
P
S
R
R
V
F
N
P
Y
Chimpanzee
Pan troglodytes
XP_001156210
410
44344
S246
I
G
E
P
Q
S
P
S
R
R
V
F
N
P
Y
Rhesus Macaque
Macaca mulatta
Q5TM25
147
16701
A18
K
A
F
G
L
L
K
A
Q
Q
E
E
R
L
D
Dog
Lupus familis
XP_848956
248
27200
A81
G
T
I
A
K
S
R
A
F
G
V
C
S
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9D8Y0
240
26773
S76
I
G
E
P
Q
S
P
S
R
R
V
F
N
P
Y
Rat
Rattus norvegicus
Q4FZY0
239
26741
S75
I
G
E
P
Q
S
P
S
R
R
V
F
N
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518105
170
19250
G40
Q
Y
D
A
G
R
D
G
F
I
D
L
M
E
L
Chicken
Gallus gallus
P09860
161
18412
E32
D
I
F
V
L
G
A
E
D
G
C
I
S
T
K
Frog
Xenopus laevis
NP_001089944
202
23367
R63
K
D
M
E
Q
M
F
R
Q
F
D
A
G
H
D
Zebra Danio
Brachydanio rerio
NP_001038676
233
26492
S69
V
G
E
H
Q
Q
P
S
M
K
V
F
N
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VJ26
217
25068
F63
V
V
N
V
Y
T
D
F
P
E
F
S
R
N
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001176294
193
22506
F62
Y
D
T
G
G
D
N
F
I
D
M
M
E
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9LQN4
166
18399
L37
G
S
L
T
Q
L
E
L
G
S
L
L
R
A
L
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58
25.8
62
N.A.
94.1
93.3
N.A.
60
20
70.4
75
N.A.
45.8
N.A.
N.A.
53.3
Protein Similarity:
100
58.2
37.9
68.9
N.A.
97
96.6
N.A.
64.1
38.7
76.6
83.7
N.A.
60.8
N.A.
N.A.
63.7
P-Site Identity:
100
100
0
20
N.A.
100
100
N.A.
0
0
6.6
66.6
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
100
20
40
N.A.
100
100
N.A.
6.6
6.6
13.3
80
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
22
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
36.2
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
0
16
0
0
8
16
0
0
0
8
0
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% C
% Asp:
8
16
8
0
0
8
16
0
8
8
16
0
0
0
16
% D
% Glu:
0
0
39
8
0
0
8
8
0
8
8
8
8
8
0
% E
% Phe:
0
0
16
0
0
0
8
16
16
8
8
39
0
0
0
% F
% Gly:
16
39
0
16
16
8
0
8
8
16
0
0
8
0
8
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% H
% Ile:
31
8
8
0
0
0
0
0
8
8
0
8
0
0
0
% I
% Lys:
16
0
0
0
8
0
8
0
0
8
0
0
0
0
16
% K
% Leu:
0
0
8
0
16
16
0
8
0
0
8
16
0
16
16
% L
% Met:
0
0
8
0
0
8
0
0
8
0
8
8
8
0
0
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
0
0
39
8
0
% N
% Pro:
0
0
0
31
0
0
39
0
8
0
0
0
0
47
0
% P
% Gln:
8
0
0
0
54
8
0
0
16
8
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
8
8
31
31
0
0
24
0
0
% R
% Ser:
0
8
0
0
0
39
0
39
0
8
0
8
16
0
0
% S
% Thr:
0
8
8
8
0
8
0
0
0
0
0
0
0
8
0
% T
% Val:
16
8
0
16
0
0
0
0
0
0
47
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
0
0
8
0
0
0
0
0
0
0
0
0
39
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _